Resveratrol vs. trans-resveratrol
Dear Stephen,
I have been working my way up through the Buhner core lyme protocol during the past few months. I have extreme chemical sensitivity (from toxic molds) and cannot tolerate the Source Naturals resveratrol because of the binders and fillers. Instead I am using the Pure Encapsulations version, but don’t know how the dosage compares, since it says “standardized to contain 20% transresveratrol — 40mg/capsule”. The company told me that what I need is the “trans” version… is that correct? If so, is the amount of trans-resveratrol to be taken the same as the amount of resveratrol you recommend?
I have been working my way up through the Buhner core lyme protocol during the past few months. I have extreme chemical sensitivity (from toxic molds) and cannot tolerate the Source Naturals resveratrol because of the binders and fillers. Instead I am using the Pure Encapsulations version, but don’t know how the dosage compares, since it says “standardized to contain 20% transresveratrol — 40mg/capsule”. The company told me that what I need is the “trans” version… is that correct? If so, is the amount of trans-resveratrol to be taken the same as the amount of resveratrol you recommend?
Also, the wholistic pharmacy told me that Resveratrol is contraindicated when antifungals (I’m on sporanox and nystatin) are being used, per the Natural Medicines Comprehensive Database. That volume also mentions problems with resveratrol being a phytoestrogen and not recommended in cases of hormone-based cancers (such as ovarian).
Stephen’s response:
What you really need to be taking is Japanese knotweed root. That root contains resveratrol, trans-resveratrol and other wonderful constituents, all of which are useful for lyme. And, no, it is not correct that you need the trans version. Further, the estrogenic actions of resveratrol occur primarily in isolation rather than in whole root form which contains a lot of things besides resveratrol. And no, knotweed root is not contraindicated with antifungals. The Source Naturals form of the caplet that I recommend is recommended because it is essential whole root knotweed that is standardized to contain a certain percentage of resveratrol. What I would recommend is that you get the whole root in encapsulated form. You can get it from Tim Scott at tim@greendragonbotanicals.com in Bratteleboro, VT.
What you really need to be taking is Japanese knotweed root. That root contains resveratrol, trans-resveratrol and other wonderful constituents, all of which are useful for lyme. And, no, it is not correct that you need the trans version. Further, the estrogenic actions of resveratrol occur primarily in isolation rather than in whole root form which contains a lot of things besides resveratrol. And no, knotweed root is not contraindicated with antifungals. The Source Naturals form of the caplet that I recommend is recommended because it is essential whole root knotweed that is standardized to contain a certain percentage of resveratrol. What I would recommend is that you get the whole root in encapsulated form. You can get it from Tim Scott at tim@greendragonbotanicals.com in Bratteleboro, VT.
Stephen
posted on January 11, 2010 in Herbs, japanese knotweed
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